What is Postpartum heamorrhage?


Postpartum bleeding or postpartum haemorrhage (PPH) is often defined as the loss of more than 500 ml (at vaginal birth) or 1,000 ml (at caesarean section) of blood within the first 24 hours following childbirth.

Excessive bleeding after childbirth, usually known as PPH is a leading cause of maternal mortality and morbidity.  PPH follows 6% to 10% of all births and accounts for around 100,000 maternal deaths every year. Ninety-nine percent of deaths are in low and middle income countries (LMICs). Many women who survive experience severe morbidity. Some women need surgery to control the bleeding (e.g. exploratory laparotomy, uterine artery ligation, brace sutures) and many require a hysterectomy, thus removing the possibility of having more children. Severe morbidity due to PPH interferes with breastfeeding and bonding.

The WOMAN-2 trial will provide reliable evidence on the effect of tranexamic acid (TXA) on preventing PPH.

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